4-[N,N-bis(2-Hydroxyethyl)amino]benzaldehyde(CAS: 27913-86-6)

4-[N,N-bis(2-Hydroxyethyl)amino]benzaldehyde (CAS: 27913-86-6) is a white crystalline solid with a molecular weight of approximately 245.24 g/mol. It is soluble in water and ethanol. The compound is moderately reactive, showing susceptibility to nucleophilic substitution and condensation reactions. It has a pKa of around 10.5, indicating basic properties.

4-[N,N-bis(2-Hydroxyethyl)amino]benzaldehyde (CAS: 27913-86-6) can be synthesized via the condensation of benzaldehyde with 2-hydroxyethylamine. A common method involves the use of anhydrous ethanol as a solvent and p-toluenesulfonic acid (PTSA) as a catalyst. The reaction is typically performed under mild conditions to achieve high selectivity and yield.

4-[N,N-bis(2-Hydroxyethyl)amino]benzaldehyde (CAS: 27913-86-6) is used in various industries. It is a key intermediate in the production of pharmaceuticals, particularly in the synthesis of certain drugs. It also finds applications in the development of sensors and semiconductors due to its functional groups.

When handling 4-[N,N-bis(2-Hydroxyethyl)amino]benzaldehyde (CAS: 27913-86-6), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat. Ensure that the work is conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Proper disposal should be done according to local regulations, and spills should be cleaned up immediately following the manufacturer's safety data sheet (SDS) guidelines.