4-Bromo-6-methyl-1H-indazole(CAS: 885521-94-8)

4-Bromo-6-methyl-1H-indazole is a crystalline solid with a molecular weight of approximately 229.04 g/mol. It has a low solubility in water but is soluble in organic solvents such as ethanol and acetone. Chemically, it exhibits moderate reactivity, especially towards nucleophiles, and can form stable complexes with metal ions.

4-Bromo-6-methyl-1H-indazole can be synthesized via a bromination reaction of 6-methyl-1H-indazole. The bromination is typically catalyzed by N-bromosuccinimide (NBS) in the presence of an organic solvent such as chloroform. The reaction yields a high purity product with good selectivity and yield.

4-Bromo-6-methyl-1H-indazole finds applications in the pharmaceutical and chemical industries, particularly in the synthesis of intermediates for drug development. It is also used in the preparation of functional materials for sensors and semiconductors.

When handling 4-Bromo-6-methyl-1H-indazole, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and ignition sources. In case of a spill, it should be carefully cleaned up using appropriate procedures, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for specific safety instructions.