Methyl 2-bromo-5-chloro-N-(2-hydroxy-4-methylpentanoyl)phenylalaninate(CAS: 90045-23-1)

Methyl 2-bromo-5-chloro-N-(2-hydroxy-4-methylpentanoyl)phenylalaninate is a white crystalline solid at room temperature. It has a molecular weight of approximately 436.15 g/mol and is moderately soluble in organic solvents. The compound is reactive towards nucleophiles due to the presence of the bromine and chloro substituents. It is also susceptible to hydrolysis under basic conditions.

Methyl 2-bromo-5-chloro-N-(2-hydroxy-4-methylpentanoyl)phenylalaninate is typically synthesized via a multistep process involving bromination and chlorination of a phenylalanine derivative, followed by esterification. The reaction is catalyzed by Lewis acids and proceeds with good yield and selectivity.

Methyl 2-bromo-5-chloro-N-(2-hydroxy-4-methylpentanoyl)phenylalaninate is used in the pharmaceutical industry for the synthesis of certain drug intermediates. It also has potential applications in the polymer and sensor industries due to its chemical reactivity and functional groups.

Proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat is necessary when handling Methyl 2-bromo-5-chloro-N-(2-hydroxy-4-methylpentanoyl)phenylalaninate. It should be stored in a cool, dry place away from direct sunlight and incompatible substances. In case of spill, it should be handled according to the Material Safety Data Sheet (MSDS) guidelines.