6-Bromo-1-indanecarbonitrile(CAS: 783335-58-0)

6-Bromo-1-indanecarbonitrile (CAS: 783335-58-0) is a crystalline solid with a molecular weight of approximately 228.04 g/mol. It has a low solubility in water but is soluble in organic solvents like acetone and dichloromethane. The compound is moderately reactive, particularly towards nucleophilic substitution reactions. It displays weak basicity and can undergo ring-opening reactions under certain conditions.

6-Bromo-1-indanecarbonitrile is typically synthesized through the bromination of 1-indanecarbonitrile using N-bromosuccinimide (NBS) as a brominating agent in the presence of a photoinitiator. The reaction occurs under UV light, providing good yields and selectivity. Other methods involve using phosphorus oxybromide (POBr3) or other brominating reagents under different reaction conditions.

6-Bromo-1-indanecarbonitrile (CAS: 783335-58-0) is primarily used in the pharmaceutical and fine chemical industries for the synthesis of intermediates. It also finds applications in polymer science, where it can be used as a monomer or additive, and in sensor technology due to its reactivity and stability.

Handling 6-Bromo-1-indanecarbonitrile (CAS: 783335-58-0) requires appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Ensure the use of a fume hood during handling to minimize exposure. Spills should be cleaned up using appropriate absorbent materials and rinsed with water. Always consult the Material Safety Data Sheet (MSDS) for detailed handling and safety procedures.