1H-Indene-1,2(3H)-dione(CAS: 16214-27-0)

1H-Indene-1,2(3H)-dione is a solid with a crystalline form. Its molecular weight is approximately 144.15 g/mol. It has low water solubility and good solubility in organic solvents. Chemically, it is reactive towards nucleophiles and electrophiles, making it useful for various synthetic transformations.

1H-Indene-1,2(3H)-dione can be synthesized through the dehydration of 1,2-dihydroindene using conditions such as concentrated sulfuric acid at elevated temperatures. Other methods involve the oxidation of indene with oxygen in the presence of a catalyst, often leading to high selectivity and yield.

1H-Indene-1,2(3H)-dione is primarily used in the pharmaceutical and polymer industries. It serves as a precursor in the synthesis of certain drugs and is also utilized in the production of plasticizers and other chemical intermediates.

When handling 1H-Indene-1,2(3H)-dione, it is essential to wear appropriate personal protective equipment (PPE), including gloves and goggles. It should be stored in a cool, dry place, away from heat sources and oxidizing agents. Fume hoods should be used during all operations to minimize exposure to vapors. Always refer to the safety data sheet (SDS) for detailed information on handling and storage.