1-(5-Bromo-4-methyl-2-thienyl)ethanone(CAS: 859199-06-7)

1-(5-Bromo-4-methyl-2-thienyl)ethanone (CAS: 859199-06-7) is a crystalline solid with a molecular weight of approximately 256.0 g/mol. It is slightly soluble in water but has better solubility in organic solvents like ethanol and acetone. The compound is known for its reactivity towards nucleophiles and its resistance to oxidation. It maintains stability under normal storage conditions but should be handled with care due to its potential reactivity.

1-(5-Bromo-4-methyl-2-thienyl)ethanone (CAS: 859199-06-7) is typically synthesized via the condensation of 4-methylthiophenol with acetyl chloride in the presence of a phase-transfer catalyst. The reaction is carried out under mild conditions, and the yield is around 85%. The use of a suitable catalyst ensures high selectivity and yields a pure product.

1-(5-Bromo-4-methyl-2-thienyl)ethanone (CAS: 859199-06-7) is used in the pharmaceutical and polymer industries. It serves as a precursor for the synthesis of various medications and is also incorporated into polymer matrices to enhance their properties. Additionally, it is utilized in the development of sensors and semiconductors due to its unique chemical reactivity.

When handling 1-(5-Bromo-4-methyl-2-thienyl)ethanone (CAS: 859199-06-7), appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the Material Safety Data Sheet (MSDS) for specific safety guidelines and emergency procedures.