Sodium 2,6-dioxo-1,2,3,6-tetrahydropurin-7-ide(CAS: 1196-43-6)

Sodium 2,6-dioxo-1,2,3,6-tetrahydropurin-7-ide is a crystalline solid with a molecular weight of approximately 268.17 g/mol. It has a melting point of about 205-208°C. The compound is slightly soluble in water and ethanol. It exhibits moderate reactivity, showing some tendency to hydrolyze in aqueous solutions. It is a useful intermediate in organic synthesis and has limited solubility in common organic solvents.

Sodium 2,6-dioxo-1,2,3,6-tetrahydropurin-7-ide is typically synthesized from 2,6-dioxo-1,2,3,6-tetrahydropurine-7-carboxylic acid using sodium hydroxide in a solution. The reaction involves the deprotonation of the carboxylic acid group, followed by the formation of the corresponding sodium salt. The yield is usually around 85-90%, and the reaction is carried out under mild conditions to ensure high selectivity.

Sodium 2,6-dioxo-1,2,3,6-tetrahydropurin-7-ide is primarily used in the pharmaceutical industry as an intermediate for the production of purine derivatives, which are important in the treatment of various diseases such as gout and cancer. It is also used in the research and development sector for the synthesis of new drugs and in the chemical industry for the production of certain organic compounds.

When handling Sodium 2,6-dioxo-1,2,3,6-tetrahydropurin-7-ide, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a fume hood due to its potential to release harmful vapors. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed information on handling, storage, and disposal procedures to ensure safe laboratory practices.