3-Methylenedihydro-2(3H)-furanone(CAS: 547-65-9)

3-Methylenedihydro-2(3H)-furanone is a colorless or white crystalline solid with a molecular weight of approximately 122.12 g/mol. It has a low solubility in water but is soluble in organic solvents such as ethanol. This compound is relatively stable under normal conditions but can react with strong bases or oxidizers. It is an important intermediate in various chemical syntheses.

3-Methylenedihydro-2(3H)-furanone is typically synthesized via the Wittig reaction using methyl vinyl ketone and sodium bis(trimethylsilyl)amide (sodium bis(trimethylsilyl)amide). This method provides a high yield and good selectivity. Other routes include the reaction of furanone with methylene chloride in the presence of a suitable catalyst.

3-Methylenedihydro-2(3H)-furanone is used in the pharmaceutical industry for the synthesis of certain drugs. It is also applied in the polymer industry as a monomer. Additionally, it plays a role in the development of sensors and semiconductors due to its unique chemical properties.

Proper personal protective equipment (PPE) such as gloves and goggles should be worn when handling 3-Methylenedihydro-2(3H)-furanone. It should be stored in a cool, dry place, away from oxidizers and strong bases. In case of spill, it should be handled in a fume hood, and appropriate safety data sheet (SDS) should be consulted for detailed handling instructions.