4-(2-Methoxyethoxy)benzonitrile(CAS: 80407-66-5)

4-(2-Methoxyethoxy)benzonitrile is a colorless liquid with a CAS number of 80407-66-5. It has a molecular weight of approximately 228.22 g/mol and a boiling point of 147-148°C. The compound is slightly soluble in water but highly soluble in organic solvents. It is reactive towards nucleophiles and can undergo various substitution and addition reactions.

4-(2-Methoxyethoxy)benzonitrile is typically synthesized through the reaction of 2-methoxyethanol with benzonitrile in the presence of a base like sodium hydride. The reaction is carried out at room temperature, providing a yield of around 75-80%. The key to the reaction is the use of a suitable base to facilitate the nucleophilic substitution reaction.

4-(2-Methoxyethoxy)benzonitrile is used in various industries including pharmaceuticals, where it serves as a precursor for drug synthesis; in polymer chemistry, as a monomer or modifier; and in the production of sensors and semiconductors, where its chemical properties make it suitable for specific applications.

When handling 4-(2-Methoxyethoxy)benzonitrile (CAS: 80407-66-5), appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. This compound is flammable and reactive, so it should be stored in a cool, dry place away from sources of ignition. In case of a spill, it should be contained and disposed of according to the Material Safety Data Sheet (MSDS) guidelines. Always refer to the SDS for detailed safety information.