5-(Aminomethyl)nicotinaldehyde(CAS: 887579-82-0)

5-(Aminomethyl)nicotinaldehyde is a white crystalline solid with a molecular weight of approximately 185.19 g/mol. It is slightly soluble in water and ethanol. Chemically, it is highly reactive, particularly towards nucleophilic substitution and condensation reactions.

5-(Aminomethyl)nicotinaldehyde can be synthesized via the condensation of nicotinaldehyde with an amine such as methylamine. The reaction typically requires a catalyst like boron trifluoride etherate and is conducted under mild conditions to achieve high selectivity and yield.

5-(Aminomethyl)nicotinaldehyde is used in the pharmaceutical industry for the synthesis of certain active pharmaceutical ingredients. It is also employed in the sensor and semiconductor industries for the development of reagents and materials.

When handling 5-(Aminomethyl)nicotinaldehyde, it is essential to wear appropriate personal protective equipment (PPE), including gloves and goggles. The compound should be handled in a well-ventilated area or fume hood. Spills should be cleaned up with care, and the Material Safety Data Sheet (MSDS) should be consulted for detailed spill procedures.