1-{2-[4-(Chloromethyl)phenoxy]ethyl}azepane(CAS: 212771-30-7)

1-{2-[4-(Chloromethyl)phenoxy]ethyl}azepane is a colorless to light yellow oil with a molecular weight of approximately 315.25 g/mol. It has a low solubility in water but is soluble in organic solvents such as ethanol and dichloromethane. It exhibits moderate reactivity, particularly towards nucleophiles, and can undergo substitution reactions. It crystallizes in the form of a white solid at low temperatures.

1-{2-[4-(Chloromethyl)phenoxy]ethyl}azepane is typically synthesized through a multi-step process involving the coupling of a chloromethylated phenol with azepane using a suitable base as a catalyst. The reaction is carried out in an organic solvent at a controlled temperature, leading to a high yield of the desired product with good functional group compatibility.

1-{2-[4-(Chloromethyl)phenoxy]ethyl}azepane is primarily used in pharmaceuticals for its potential as an intermediate in drug synthesis. It may also be used in the production of polymers and as a component in sensors and semiconductor materials due to its unique chemical properties.

When handling 1-{2-[4-(Chloromethyl)phenoxy]ethyl}azepane, it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Ensure the use of a fume hood to minimize exposure to volatile components. Store the compound in a cool, dry place away from direct sunlight and incompatible materials. In case of a spill, follow the safety data sheet (SDS) guidelines for proper disposal.