Methyl 4-Bromocrotonate, 85%(CAS: 1117-71-1)

Methyl 4-Bromocrotonate is a crystalline compound with a molecular weight of approximately 211.03 g/mol. It has a solubility of about 0.5 g/L in water and is sparingly soluble in ethanol. Chemically, it is reactive towards nucleophiles and undergoes bromocrotonate ester hydrolysis. It is used in organic synthesis and as a precursor in polymer chemistry.

Methyl 4-Bromocrotonate is typically synthesized by the bromination of crotonic acid in the presence of an appropriate base. Commonly, this involves a nucleophilic substitution reaction where bromine reacts with crotonic acid to form the bromo derivative, followed by esterification with methanol. The yield is around 85%, and the reaction is usually performed under mild conditions.

Methyl 4-Bromocrotonate is primarily used in the pharmaceutical and polymer industries. It serves as a key intermediate for the synthesis of various drugs and is also used in the production of functional polymers. Additionally, it has applications in semiconductor and sensor technologies due to its reactivity and stability.

When handling Methyl 4-Bromocrotonate, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a well-ventilated area and away from heat sources. Spills should be handled using appropriate safety protocols and clean-up materials. Always refer to the Safety Data Sheet (SDS) for detailed safety information.