1-(Phenylsulfonyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole(CAS: 870717-93-4)

1-(Phenylsulfonyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole is a crystalline compound with a molecular weight of approximately 404.35 g/mol. It has limited aqueous solubility. This compound is reactive towards nucleophiles and can undergo various chemical transformations. It is stable under normal conditions but should be stored in a dry, cool place away from direct sunlight.

1-(Phenylsulfonyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole can be synthesized using a Suzuki coupling reaction. The key steps involve the formation of the boronic acid ester, followed by its coupling with the phenylsulfonyl indole. Common catalysts include palladium(0) complexes, and the reaction typically proceeds with good yield under mild conditions.

1-(Phenylsulfonyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole finds applications in the pharmaceutical and fine chemical industries. It is used as an intermediate in the synthesis of drugs and as a building block for functional materials. Its unique structure allows for its use in developing new materials and pharmaceuticals.

When handling 1-(Phenylsulfonyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a fume hood to minimize inhalation risks. Spills should be cleaned up immediately with an appropriate absorbent material, followed by thorough ventilation. Refer to the material safety data sheet (MSDS) for detailed safety information and emergency procedures.