1-(5-Phenyl-3-pyridinyl)-1,4-diazepane(CAS: 223796-38-1)

1-(5-Phenyl-3-pyridinyl)-1,4-diazepane (CAS: 223796-38-1) is a crystalline solid with a molecular weight of approximately 254.25 g/mol. It has a high solubility in polar solvents such as dimethylformamide and methanol. Chemically, it is relatively stable and reacts with electrophiles, particularly under basic conditions. This compound is a versatile building block in medicinal chemistry and organic synthesis.

1-(5-Phenyl-3-pyridinyl)-1,4-diazepane is typically synthesized through a multistep process involving the reaction of 5-phenyl-3-pyridinone with morpholine. The key steps include the condensation of the pyridone with morpholine followed by amination to form the diazepane ring. This process often requires mild basic conditions and is carried out with high selectivity and yield, typically over 90%.

1-(5-Phenyl-3-pyridinyl)-1,4-diazepane (CAS: 223796-38-1) finds applications in the pharmaceutical industry due to its potential as a drug candidate. It is also utilized in the synthesis of polymers and as a ligand in coordination chemistry. Its use in sensors and semiconductors is limited but promising, particularly for its stability and reactivity.

When handling 1-(5-Phenyl-3-pyridinyl)-1,4-diazepane (CAS: 223796-38-1), it is essential to wear appropriate personal protective equipment (PPE) such as gloves and lab coat. Store it in a fume hood to avoid inhalation. Handle it with care to prevent skin contact. In case of spill, immediately clean up with appropriate absorbent material and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.