m-Cyanoacetophenone(CAS: 6136-68-1)

m-Cyanoacetophenone (CAS: 6136-68-1) is a crystalline solid with a molecular weight of approximately 142.12 g/mol. It has a melting point of 60-62°C and is slightly soluble in water but more soluble in organic solvents such as ethanol, acetone, and dichloromethane. It reacts readily with nucleophiles due to the presence of the cyano group, showing good reactivity in chemical synthesis.

m-Cyanoacetophenone (CAS: 6136-68-1) is commonly synthesized via the reaction of acetophenone and carbon monoxide in the presence of a metal catalyst such as rhodium or palladium under pressure. The yield is usually high, and the reaction is selective, producing the desired product with good purity.

m-Cyanoacetophenone (CAS: 6136-68-1) is used in various industries, including pharmaceuticals, where it serves as a precursor for drug synthesis, and in the production of polymers and semiconductors. It also finds applications in the development of chemical sensors and as a reagent in various analytical techniques.

When handling m-Cyanoacetophenone (CAS: 6136-68-1), it is essential to use appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. The substance should be stored in a cool, dry place, away from direct sunlight and heat sources. In case of a spill, it should be handled using appropriate spill control measures, and care should be taken to avoid inhalation or skin contact. Always consult the Safety Data Sheet (SDS) for detailed handling and safety information.