2-[(5-Chloro-2-{[2-methoxy-4-(4-morpholinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzamide(CAS: 761437-28-9)

This compound is a white to off-white solid with a molecular weight of approximately 536.9 g/mol. It is slightly soluble in water but more soluble in organic solvents like DMSO and DMF. The compound is reactive towards nucleophiles and can undergo substitution reactions. It is not flammable but may decompose under strong heat conditions.

The compound is synthesized via a multi-step process involving the coupling of a pyrimidine derivative with a morpholine-containing aromatic amine. The key steps include nucleophilic aromatic substitution and amidation reactions, yielding a high yield with good selectivity. Catalysts such as EDC and HOBT are commonly used.

This compound is primarily used in the pharmaceutical industry for its potential as an anti-inflammatory agent. It is also explored in sensor and semiconductor applications due to its chemical stability and reactivity.

When handling this compound, wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood. Avoid contact with skin and eyes. In case of spill, sweep up and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.