Methyl 2-pyrimidinecarboxylate(CAS: 34253-03-7)

Methyl 2-pyrimidinecarboxylate (CAS: 34253-03-7) is a crystalline solid with a molecular weight of approximately 149.13 g/mol. It has a solubility of 6.5 g/100 mL in water and is slightly soluble in many organic solvents. Chemically, it is known to react readily with bases, forming pyrimidine-2-carboxylate salts, and is stable under normal laboratory conditions.

Methyl 2-pyrimidinecarboxylate (CAS: 34253-03-7) can be synthesized via the reaction of 2-pyrimidinecarboxylic acid with methyl alcohol in the presence of a catalytic amount of sulfuric acid. The reaction is carried out under reflux for several hours, followed by recrystallization from ethanol to obtain pure product.

Methyl 2-pyrimidinecarboxylate (CAS: 34253-03-7) is used in the pharmaceutical industry for the synthesis of certain drugs, as a precursor in polymer chemistry for creating advanced materials, and in sensor technologies for its ability to detect specific chemicals.

When handling Methyl 2-pyrimidinecarboxylate (CAS: 34253-03-7), it is important to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be handled with caution, using appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for detailed spill cleanup procedures.