1-{1-[4-(6-Phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)benzyl]-4-piperidinyl}-1,3-dihydro-2H-benzimidazol-2-one(CAS: 612847-09-3)

1-{1-[4-(6-Phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)benzyl]-4-piperidinyl}-1,3-dihydro-2H-benzimidazol-2-one is a crystalline compound with a molecular weight of approximately 643.5 g/mol. It has a low water solubility but is soluble in organic solvents like DMSO. The compound exhibits good stability in neutral and slightly acidic conditions, with potential reactivity towards strong acids and bases. It is an effective inhibitor of certain protein kinases, making it valuable in pharmaceutical research.

The compound is typically synthesized through a multistep process involving the reaction of 6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)benzyl] with 4-piperidinyl groups. Commonly, the synthesis involves the use of organic solvents and protecting groups to ensure the desired regioselectivity. Each step requires careful control of conditions to achieve high yield and purity. The synthetic route generally includes protecting group strategies, coupling reactions, and purification techniques such as column chromatography.

This compound is primarily used in the pharmaceutical industry for its inhibitory effects on protein kinases, which are important targets in drug discovery. It may also have applications in the polymer industry for its potential to act as a stabilizer or additive. Additionally, it could be utilized in sensor technologies due to its chemical reactivity and in semiconductor manufacturing for its stability and functional groups.

When handling 1-{1-[4-(6-Phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)benzyl]-4-piperidinyl}-1,3-dihydro-2H-benzimidazol-2-one, it is important to use personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure to the compound. Spills should be cleaned up using appropriate absorbent materials and the area should be properly ventilated. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage requirements.