(11beta)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-19-norpregna-4,9-diene-3,20-dione(CAS: 159811-51-5)

(11beta)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-19-norpregna-4,9-diene-3,20-dione is a crystalline compound with a molecular weight of approximately 422.43 g/mol. It is slightly soluble in ethanol and acetone but insoluble in water. This compound is known for its reactivity in forming esters and amides. It is generally stable under normal conditions but may degrade under strong acidic or basic conditions.

(11beta)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-19-norpregna-4,9-diene-3,20-dione is synthesized via a multi-step process involving the introduction of the amino group and hydroxylation. Commonly, this involves the use of dimethylamine, phenyl derivatives, and palladium catalysts. The synthesis typically yields over 70% purity with good regioselectivity and stereoselectivity.

(11beta)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-19-norpregna-4,9-diene-3,20-dione is primarily used in the pharmaceutical industry for its potential as a prodrug in hormone therapy. It is also explored in research for its applications in synthetic chemistry, particularly in the development of new drug candidates and in the production of certain APIs.

Precautions when handling (11beta)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-19-norpregna-4,9-diene-3,20-dione include the use of personal protective equipment (PPE) such as gloves and goggles. It should be handled in a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbents, and the area should be thoroughly rinsed with water. Users should refer to the Safety Data Sheet (SDS) for detailed information on handling and disposal.