1-(2,4-Dichlorophenyl)-1-butanone(CAS: 66353-47-7)

1-(2,4-Dichlorophenyl)-1-butanone (CAS: 66353-47-7) is a white crystalline solid with a molecular weight of approximately 246.06 g/mol. It has low solubility in water but is soluble in organic solvents like ethanol and acetone. This compound is moderately reactive and can undergo substitution reactions, particularly with nucleophiles.

1-(2,4-Dichlorophenyl)-1-butanone (CAS: 66353-47-7) is typically synthesized via the condensation of 2,4-dichlorophenyl isocyanide with butanal. Commonly used catalysts include acetic acid or a Lewis acid like aluminum chloride. The reaction proceeds with good yield and stoichiometric selectivity.

1-(2,4-Dichlorophenyl)-1-butanone (CAS: 66353-47-7) finds applications in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also used in the polymer industry for the modification of polymers and in the electronics sector for semiconductor applications due to its aromatic and ketone functional groups.

When handling 1-(2,4-Dichlorophenyl)-1-butanone (CAS: 66353-47-7), ensure to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood to avoid inhalation. Spills should be cleaned up immediately using appropriate absorbents, and the area should be well-ventilated. Refer to the Safety Data Sheet (SDS) for detailed information on safe handling and disposal.