(3beta)-3-Hydroxycholest-5-en-7-one(CAS: 566-28-9)

(3beta)-3-Hydroxycholest-5-en-7-one (CAS: 566-28-9) is a white crystalline solid with a molecular weight of approximately 336.46 g/mol. It is slightly soluble in chloroform and acetone but insoluble in water. The compound exhibits limited reactivity under normal conditions but can undergo oxidation and hydrolysis. It is stable under neutral and slightly acidic conditions.

(3beta)-3-Hydroxycholest-5-en-7-one (CAS: 566-28-9) is typically synthesized via the reduction of 7-one to 7-ene followed by the introduction of a hydroxyl group at the 3beta position. Common methods include catalytic hydrogenation of cholest-5-en-7-one in the presence of a palladium catalyst, followed by an alcohol formation step using sodium hydride and ethanol. This compound can also be obtained through enzymatic reactions or chemical modifications of cholesterol derivatives.

(3beta)-3-Hydroxycholest-5-en-7-one (CAS: 566-28-9) is primarily used in the pharmaceutical industry for the synthesis of bile acid analogs and in the development of cholesterol-lowering drugs. It is also of interest in the cosmetics industry for its potential as a skin care ingredient, and in the research and development of new drug candidates for various conditions involving cholesterol metabolism.

When handling (3beta)-3-Hydroxycholest-5-en-7-one (CAS: 566-28-9), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area, ideally a fume hood, to minimize exposure to the compound. Spills should be immediately cleaned up with absorbent material and disposed of according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for detailed handling and safety information.