4-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-phenylalanine(CAS: 80102-26-7)
![4-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-phenylalanine 4-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-phenylalanine](https://static.chemtradehub.com/structs/801/80102-26-7-5086.webp)
CAS Number
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Basic Information
Molecular Formula
C15H21NO4
Molecular Weight
279.34 g/mol
Physical Properties
Melting Point
84-88 °C
Boiling Point
440.4°C at 760 mmHg
Density
1.14
Flash Point
220.2°C
Water Solubility
Slightly soluble in water.
Chemical Identifiers
SMILES
CC1=CC=C(C=C1)CC(C(=O)O)NC(=O)OC(C)(C)C
InChIKey
JYRWNPUFECDJCX-LBPRGKRZSA-N
Database References
MDL Number
MFCD01317027
FAQ
4-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-phenylalanine is a crystalline solid with a molecular weight of approximately 316.4 g/mol. It has a solubility of about 100 mg/mL in water and is slightly soluble in common organic solvents. Chemically, it is stable under normal conditions but can react with strong bases. It is not flammable and has a melting point around 220°C. It is also a chiral compound with the potential for racemization under certain conditions.
4-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-phenylalanine can be synthesized via a multi-step process involving the protection of the carboxylic acid, functional group manipulation, and subsequent deprotection. Common methods include using di-tert-butyl dicarbonate for protection and TFA for deprotection. This compound is often synthesized using standard reaction conditions, such as refluxing in anhydrous methanol with a suitable catalyst, followed by purification using column chromatography or recrystallization.
4-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-phenylalanine is primarily used in the pharmaceutical industry for the synthesis of various drug candidates. It is also utilized in the polymer industry as a monomer for the synthesis of biodegradable polymers. Additionally, it has potential applications in the sensor and semiconductor industries due to its chiral nature and ability to interact with certain molecules.
When handling 4-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-phenylalanine, wear appropriate personal protective equipment (PPE) such as gloves, protective goggles, and laboratory coats. Ensure good ventilation by working in a fume hood. Store the compound in a cool, dry place away from direct sunlight and heat sources. In case of a spill, immediately clean up using appropriate absorbent materials and dispose of waste according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures

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