7-Bromo-3,4-dihydroisoquinolin-1(2H)-one(CAS: 891782-60-8)

7-Bromo-3,4-dihydroisoquinolin-1(2H)-one (CAS: 891782-60-8) is a white to off-white crystalline solid. Its molecular weight is approximately 227.04 g/mol. The compound is slightly soluble in water but soluble in organic solvents such as methanol, ethanol, and acetone. It exhibits moderate reactivity, particularly with nucleophiles and reducing agents.

7-Bromo-3,4-dihydroisoquinolin-1(2H)-one can be synthesized via bromination of 3,4-dihydroisoquinolin-1(2H)-one. Commonly, this involves the use of N-bromosuccinimide (NBS) in the presence of a suitable organic solvent like acetonitrile. The reaction typically yields a mixture that requires purification by column chromatography or recrystallization.

7-Bromo-3,4-dihydroisoquinolin-1(2H)-one (CAS: 891782-60-8) is primarily used in pharmaceuticals for the development of bioactive compounds. It also finds applications in the chemical industry for the synthesis of other valuable compounds and in the research of new materials for sensors and semiconductors.

When handling 7-Bromo-3,4-dihydroisoquinolin-1(2H)-one (CAS: 891782-60-8), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be contained and cleaned up using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for specific handling and disposal instructions.