(2S,3S)-2,3-Bis[(4-methoxybenzoyl)oxy]succinic acid(CAS: 191605-10-4)

(2S,3S)-2,3-Bis[(4-methoxybenzoyl)oxy]succinic acid is a crystalline solid with a molecular weight of approximately 540.4 g/mol. It has limited water solubility. The compound is known for its stability and reactivity in organic synthesis, particularly in coupling reactions and as a protecting group reagent.

(2S,3S)-2,3-Bis[(4-methoxybenzoyl)oxy]succinic acid is typically synthesized via a condensation reaction between succinic acid and 4-methoxybenzoyl chloride, often using a Lewis acid catalyst like aluminum trichloride. The reaction is carried out under anhydrous conditions to achieve high yields and good selectivity.

(2S,3S)-2,3-Bis[(4-methoxybenzoyl)oxy]succinic acid is used in pharmaceuticals for the protection and modification of reactive functional groups, as well as in the polymer industry for the synthesis of functionalized polymers. It is also applied in the development of sensors and semiconductor materials due to its reactivity and molecular structure.

When handling (2S,3S)-2,3-Bis[(4-methoxybenzoyl)oxy]succinic acid, use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a fume hood to avoid inhalation. Keep the compound away from heat and direct sunlight. In the case of a spill, neutralize with an appropriate base and dispose of according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.