5-Bromo-1,2,3-trimethoxybenzene(CAS: 2675-79-8)

5-Bromo-1,2,3-trimethoxybenzene (CAS: 2675-79-8) is a crystalline solid with a molecular weight of approximately 253.13 g/mol. It has a low solubility in water but is highly soluble in organic solvents like ethanol and acetone. Chemically, it is relatively unreactive under normal conditions, but it can undergo bromination and methoxy substitution reactions. Its melting point is around 122-124°C, and it is slightly soluble in water.

5-Bromo-1,2,3-trimethoxybenzene (CAS: 2675-79-8) is typically synthesized by bromination of 1,2,3-trimethoxybenzene using bromine in the presence of cupric chloride as a Lewis acid catalyst. The reaction yields a mixture of isomers, with selectivity towards the mono-brominated product. The yield is around 80-85%.

5-Bromo-1,2,3-trimethoxybenzene (CAS: 2675-79-8) is primarily used in the pharmaceutical and chemical industries for the synthesis of various organic compounds. It is also utilized in the production of dyes, polymers, and as a reagent in analytical chemistry. Its application in semiconductors and sensors is limited but exists in specialized research settings.

When handling 5-Bromo-1,2,3-trimethoxybenzene (CAS: 2675-79-8), appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. Work should be conducted in a well-ventilated area or a fume hood to avoid inhalation and skin contact. In case of a spill, it should be contained and cleaned up using appropriate absorbent materials. Immediate medical attention should be sought if any exposure occurs. Always consult the Safety Data Sheet (SDS) for detailed handling instructions.