Methyl 6-methyl-2-pyridinecarboxylate(CAS: 13602-11-4)

Methyl 6-methyl-2-pyridinecarboxylate is a white crystalline solid with a molecular weight of approximately 174.23 g/mol. It has a melting point of 86-88°C and is slightly soluble in water but miscible with organic solvents such as ethanol and acetone. It is moderately reactive towards nucleophiles and can undergo esterification and substitution reactions.

Methyl 6-methyl-2-pyridinecarboxylate can be synthesized by the esterification of 6-methyl-2-pyridinecarboxylic acid with methanol in the presence of a strong acid catalyst like sulfuric acid. The reaction typically proceeds with good yield and high selectivity towards the desired ester product.

Methyl 6-methyl-2-pyridinecarboxylate is used in the pharmaceutical industry as a precursor for the synthesis of certain drugs. It is also utilized in the polymer industry as a monomer and in the production of sensors for various applications. Additionally, it has found use in the semiconductor industry for specific chemical processes.

When handling Methyl 6-methyl-2-pyridinecarboxylate, proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. It should be handled in a well-ventilated area or in a fume hood to prevent inhalation. Spills should be cleaned up using appropriate absorbents, and the area should be thoroughly washed down. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.