3-Methylidene-7-(pyrazolo[1,5-a]pyridine-3-carbonyl)-2,7-diazaspiro[4.4]nonan-1-one(CAS: 943609-66-3)

3-Methylidene-7-(pyrazolo[1,5-a]pyridine-3-carbonyl)-2,7-diazaspiro[4.4]nonan-1-one is a white solid with a high melting point and a molecular weight of approximately 367.37 g/mol. It has poor water solubility but is soluble in organic solvents like DMSO and DMF. Chemically, it is relatively stable but can react with strong bases and reducing agents. It exhibits moderate reactivity in organic synthesis due to its functional groups.

3-Methylidene-7-(pyrazolo[1,5-a]pyridine-3-carbonyl)-2,7-diazaspiro[4.4]nonan-1-one is typically synthesized via multistep reactions involving condensation and ring formation. Commonly, a pyridine derivative and a diazainonane undergo a condensation reaction in the presence of a catalyst such as HATU. The process yields a high purity product with good selectivity and yield, usually around 80-90%.

3-Methylidene-7-(pyrazolo[1,5-a]pyridine-3-carbonyl)-2,7-diazaspiro[4.4]nonan-1-one is used primarily in the pharmaceutical industry for the development of novel drug candidates. It can also find applications in polymer synthesis and the production of advanced materials. Additionally, it may be used in the development of chemical sensors and as a building block in organic synthesis.

When handling 3-Methylidene-7-(pyrazolo[1,5-a]pyridine-3-carbonyl)-2,7-diazaspiro[4.4]nonan-1-one, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coat. Ensure the work is conducted in a well-ventilated fume hood. Spills should be cleaned up using appropriate absorbents, and the area should be flushed with water. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.