Methyl 3-chloro-3-oxopropanoate(CAS: 37517-81-0)

Methyl 3-chloro-3-oxopropanoate (CAS: 37517-81-0) is a white crystalline solid with a molecular weight of approximately 137.56 g/mol. It has a high melting point around 138°C and a low solubility in water. It is slightly soluble in ethanol and acetone. Chemically, it is highly reactive, particularly towards nucleophiles and reducing agents.

Methyl 3-chloro-3-oxopropanoate (CAS: 37517-81-0) can be synthesized via the chlorination of methyl acetate using thionyl chloride in the presence of a drying agent. The reaction is typically carried out under anhydrous conditions to ensure high yield and selectivity.

Methyl 3-chloro-3-oxopropanoate (CAS: 37517-81-0) is used in the pharmaceutical industry for the synthesis of various drug intermediates. It is also utilized in the polymer industry for modifying polymer properties and in the semiconductor industry for the production of photoresists. Additionally, it serves as a key component in the development of chemical sensors.

When handling Methyl 3-chloro-3-oxopropanoate (CAS: 37517-81-0), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Handle in a well-ventilated environment or a fume hood. Store in a cool, dry place away from heat sources. In case of spill, neutralize with an appropriate solvent and dispose of according to local regulations. Always refer to the safety data sheet (SDS) for detailed safety information.