4-Bromo-6-methoxy-1H-indazole(CAS: 885520-83-2)

4-Bromo-6-methoxy-1H-indazole is a solid compound with a crystalline form. Its molecular weight is approximately 250.02 g/mol. It has moderate solubility in common organic solvents like ethanol and acetone. Chemically, it exhibits moderate reactivity towards nucleophiles and electrophiles. It is stable under normal conditions but should be stored away from strong oxidizing agents.

4-Bromo-6-methoxy-1H-indazole is typically synthesized via a bromination reaction of 4-methoxy-1H-indazole with bromine in the presence of a phase transfer catalyst. The reaction proceeds with good yield, and the product can be purified by recrystallization from ethanol. The reaction is selective and efficient under these conditions.

4-Bromo-6-methoxy-1H-indazole is used in the pharmaceutical industry for the synthesis of certain drug candidates. It is also utilized in the semiconductor industry for the fabrication of electronic devices due to its unique electronic properties. Additionally, it has potential applications in sensor development and as a precursor in polymer chemistry.

When handling 4-Bromo-6-methoxy-1H-indazole, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Ensure that the work is conducted in a well-ventilated fume hood to minimize the risk of inhalation. Spills should be cleaned up immediately using appropriate absorbents, and the area should be thoroughly decontaminated. Always consult the Safety Data Sheet (SDS) for detailed emergency procedures.