3-Amino-5-chlorobenzoic acid(CAS: 21961-30-8)

3-Amino-5-chlorobenzoic acid (CAS: 21961-30-8) is a solid compound with a crystalline form. Its molecular weight is approximately 213.58 g/mol. It has a solubility of about 1.7 g/L in water at 25°C. This compound is moderately reactive, showing some basic properties due to the amino group. It is also susceptible to hydrolysis under basic conditions.

3-Amino-5-chlorobenzoic acid is typically synthesized via the aminoalkylation of 5-chlorobenzoic acid with an amine compound. Common methods include the use of hydroxylamine hydrochloride in aqueous acetic acid, followed by hydrolysis and purification. The yield is generally around 70-80%, and the reaction is highly selective.

3-Amino-5-chlorobenzoic acid (CAS: 21961-30-8) is primarily used in the pharmaceutical and chemical industries. It is a key intermediate in the synthesis of various drugs and also finds applications in the development of sensors and materials, particularly in the field of semiconductors.

When handling 3-Amino-5-chlorobenzoic acid (CAS: 21961-30-8), appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. Work should be conducted in a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbent materials and waste disposed of according to local regulations. Safety data sheets (SDS) should be consulted for detailed information on handling and storage.