4,4-Difluorocyclohexanone(CAS: 22515-18-0)

4,4-Difluorocyclohexanone (CAS: 22515-18-0) is a colorless liquid with a fruity odor. It has a molecular weight of 148.06 g/mol. The compound is moderately soluble in water but miscible with ethanol and ether. Chemically, it is reactive towards nucleophiles and can undergo various organic transformations like esterification and nucleophilic substitution.

4,4-Difluorocyclohexanone can be synthesized via the oxidation of 4,4-difluorocyclohexanol using a suitable oxidizing agent. Common methods include the use of ammonium persulfate or osmium tetroxide. The yield is typically high, and the reaction is selective for the desired product.

4,4-Difluorocyclohexanone is used in the pharmaceutical, polymer, and chemical industries. It serves as a precursor in the synthesis of drugs, functional polymers, and as a building block in organic chemistry. Its use in sensors and semiconductors is also explored due to its chemical stability and reactivity.

When handling 4,4-Difluorocyclohexanone (CAS: 22515-18-0), it is crucial to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Store the compound in a fume hood and avoid contact with skin and eyes. In case of a spill, follow standard safety procedures and refer to the Material Safety Data Sheet (MSDS) for detailed instructions.