1-(3-Chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)ethanone(CAS: 25961-11-9)

1-(3-Chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)ethanone is a crystalline compound with a molecular weight of approximately 313.03 g/mol. It has low water solubility and is soluble in organic solvents such as dichloromethane and acetonitrile. The compound is reactive, particularly towards nucleophilic substitution reactions. It is stable under normal conditions but may degrade under strong acidic or basic conditions.

1-(3-Chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)ethanone is typically synthesized via a multi-step process involving the reaction of 5-chloro-10,11-dihydro-5H-dibenzo[b,f]azepine with ethyl chloroformate. The reaction is carried out in the presence of a base such as triethylamine. The yield is moderate, and the reaction is selective for the desired product.

1-(3-Chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)ethanone is used in the pharmaceutical industry for the synthesis of certain drugs. It is also employed in the development of materials for sensors and semiconductors due to its unique chemical properties.

When handling 1-(3-Chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)ethanone, it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. The compound should be handled in a fume hood to minimize inhalation. Spills should be cleaned up with appropriate absorbent materials and disposed of according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for specific safety information.