2-Methyl-2-propanyl 2-bromoacrylate(CAS: 79762-78-0)

2-Methyl-2-propanyl 2-bromoacrylate is a colorless to pale yellow liquid. Its molecular weight is approximately 184.05 g/mol. It has a low solubility in water (less than 1 g/L at 20°C) but is readily soluble in organic solvents like ethanol and acetone. The compound is reactive towards nucleophiles and can undergo polymerization under certain conditions.

2-Methyl-2-propanyl 2-bromoacrylate is synthesized via the bromination of 2-methyl-2-propanoic acid ethyl ester. The bromination reaction is typically carried out in the presence of a Lewis acid catalyst, such as aluminum bromide, at a temperature range of 0 to 10°C. This process provides high yield and excellent selectivity for the bromoacrylate product.

2-Methyl-2-propanyl 2-bromoacrylate is used in several industries. It is a key intermediate in the production of polymers, particularly in the synthesis of polyacrylates. It also finds applications in the pharmaceutical industry for the synthesis of certain drug intermediates, and in the production of sensors and semiconductors due to its reactivity and functional groups.

When handling 2-Methyl-2-propanyl 2-bromoacrylate, it is crucial to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize exposure. Spills should be neutralized with an appropriate neutralizing agent and then cleaned up with absorbent material. Always consult a safety data sheet (SDS) for detailed handling and disposal instructions.