Ceritinib(CAS: 1032900-25-6)

Ceritinib is a chemical compound with the CAS number 1032900-25-6. It is a second-generation anaplastic lymphoma kinase (ALK) inhibitor used primarily in the treatment of non-small cell lung cancer (NSCLC). Ceritinib has the molecular formula C20H25N5O and exhibits good solubility in dimethyl sulfoxide (DMSO). It is known for its high potency and selectivity in targeting ALK mutations.

Ceritinib is mainly used in pharmaceutical applications as a targeted therapy for patients with ALK-positive non-small cell lung cancer (NSCLC). It is also utilized in research settings to study ALK inhibition and its effects on cancer cell proliferation. Due to its specific mechanism of action, Ceritinib finds application in clinical trials and drug development for oncology.

Ceritinib is generally considered safe when used as directed in medical and research contexts. However, it may cause side effects such as gastrointestinal issues, liver toxicity, and elevated liver enzymes. Proper handling, including the use of gloves and goggles, is recommended to ensure safety. It should be stored in a controlled environment to maintain its stability and efficacy.

Ceritinib should be stored in a cool, dry place away from direct light. It is typically kept at a temperature between 2°C to 8°C and in airtight containers to prevent moisture exposure. Proper storage conditions help maintain its chemical stability and prolong shelf life. Always follow safety guidelines when handling and storing this compound.