Ethyl 5-methyl-1,2-oxazole-3-carboxylate(CAS: 3209-72-1)

Ethyl 5-methyl-1,2-oxazole-3-carboxylate (CAS: 3209-72-1) is a white crystalline solid with a molecular weight of 164.21 g/mol. It is slightly soluble in water but soluble in common organic solvents like ethanol and acetone. Chemically, it is moderately reactive and can undergo esterification and nucleophilic substitution reactions.

Ethyl 5-methyl-1,2-oxazole-3-carboxylate (CAS: 3209-72-1) is typically synthesized by the reaction of methyl oxalyl chloride with ethylamine followed by the addition of ethyl acetoacetate. This process requires careful control of pH and temperature to ensure high yield and selectivity.

Ethyl 5-methyl-1,2-oxazole-3-carboxylate (CAS: 3209-72-1) finds applications in the pharmaceutical industry for the synthesis of various drugs, particularly those requiring oxazole derivatives. It is also used in polymer synthesis and as a precursor in semiconductor manufacturing and sensor technology.

When handling Ethyl 5-methyl-1,2-oxazole-3-carboxylate (CAS: 3209-72-1), it is important to use appropriate personal protective equipment (PPE) including gloves and goggles. Handle in a well-ventilated area or fume hood, as it is slightly irritating to skin and eyes. In case of spill, avoid direct contact and clean up using appropriate absorbent material. Refer to Safety Data Sheets (SDS) for detailed safety information.