L-Cysteinamide,N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-a-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1->6)-disulfide(CAS: 148031-34-9)

L-Cysteinamide,N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-a-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1->6)-disulfide is a cyclic peptide. It has a molecular weight of approximately 1030 g/mol. This compound is soluble in water and organic solvents like methanol and ethanol. It shows moderate reactivity, particularly towards nucleophiles and reducing agents. The cyclic disulfide linkage provides stability to the structure.

This cyclic peptide is typically synthesized through solid-phase peptide synthesis (SPPS) using standard Fmoc chemistry. The reaction involves coupling amino acids one by one, followed by removal of the Fmoc group and protection of the thiol group. The thiol is then oxidized to form the disulfide bond using oxidizing agents like iodine or sodium periodate. The final product is isolated and purified using HPLC.

L-Cysteinamide,N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-a-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1->6)-disulfide is used in the pharmaceutical industry for drug development, particularly in the synthesis of complex peptides and proteins. It also finds application in the polymer industry for the modification of polymers and in the development of smart materials. Additionally, it is used in sensor technology for the detection of specific analytes and in semiconductor industry for the synthesis of novel materials.

When handling L-Cysteinamide,N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-a-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1->6)-disulfide, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to minimize exposure to vapor and aerosols. In case of a spill, it should be carefully cleaned up using appropriate protocols, and the area should be decontaminated. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.