(3,3,3-trifluoroprop-1-en-2-yl)benzene(CAS: 384-64-5)

(3,3,3-trifluoroprop-1-en-2-yl)benzene (CAS: 384-64-5) is a colorless solid with a molecular weight of approximately 214.13 g/mol. It is slightly soluble in water but highly soluble in organic solvents like ethanol and acetone. The compound exhibits moderate reactivity with common electrophiles and nucleophiles. It crystallizes in the monoclinic system and has a melting point around 65-66°C.

(3,3,3-trifluoroprop-1-en-2-yl)benzene (CAS: 384-64-5) can be synthesized via a Friedel-Crafts alkylation reaction using trifluoropropene and benzene in the presence of a Lewis acid catalyst, such as aluminum trichloride. The reaction yields high selectivity and good to excellent yield, typically 70-90%.

(3,3,3-trifluoroprop-1-en-2-yl)benzene (CAS: 384-64-5) is used in the pharmaceutical industry for the synthesis of certain drug intermediates, in the polymer industry for the production of advanced polymers, and in semiconductor manufacturing as a precursor in chemical vapor deposition processes. It also finds applications in the development of sensors and other electronic devices.

When handling (3,3,3-trifluoroprop-1-en-2-yl)benzene (CAS: 384-64-5), it is essential to wear personal protective equipment (PPE) including gloves, goggles, and a lab coat. Ensure adequate ventilation and use a fume hood to avoid inhalation risks. Spills should be contained and cleaned up using absorbent materials, followed by disposal in accordance with local regulations. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.