3-Piperidinone hydrochloride (1:1)(CAS: 61644-00-6)

3-Piperidinone hydrochloride is a crystalline solid with a molecular weight of 165.67 g/mol. It is slightly soluble in water and ethanol. It reacts with bases to form the free base and is stable under normal ambient conditions. Its solubility in water is 1.8 g/L at 25°C.

3-Piperidinone hydrochloride is typically synthesized by the reaction of 3-piperidone with hydrochloric acid. The reaction is carried out in a solvent like methanol under reflux conditions. The yield is generally around 90%, and the product is isolated by filtration and recrystallization.

3-Piperidinone hydrochloride is used in the pharmaceutical industry as an intermediate for the synthesis of certain drugs. It is also utilized in the polymer industry for the modification of polymers and in the sensor industry for the development of gas sensors. Additionally, it has applications in the semiconductor industry as a chemical intermediate.

When handling 3-Piperidinone hydrochloride, ensure proper personal protective equipment (PPE) is worn, including gloves, safety glasses, and a lab coat. Work in a fume hood to avoid inhalation. Store the compound in a cool, dry place away from heat sources. In case of spill, neutralize with a base, then carefully dispose of the waste according to local regulations. Always consult the Safety Data Sheet (SDS) for additional safety information.