4-Sulfanylbenzoic acid(CAS: 1074-36-8)

4-Sulfanylbenzoic acid (CAS: 1074-36-8) is a white crystalline solid with a molecular weight of approximately 172.21 g/mol. It is slightly soluble in water and has a pKa around 3.8. This acid exhibits typical reactivity of carboxylic acids, including esterification and amide formation. It is also known for its reducing properties under certain conditions.

4-Sulfanylbenzoic acid can be synthesized from benzoic acid via sulfonation. This process involves treating benzoic acid with sulfur trioxide (SO3) in the presence of a solvent like methanol. Other methods include direct sulfonation of benzene followed by oxidation of the sulfide to the acid.

4-Sulfanylbenzoic acid finds applications in pharmaceuticals for use as a precursor in drug synthesis, in polymers for enhancing properties like thermal stability, and in sensors for detecting specific analytes. It also has uses in the semiconductor industry for certain cleaning and processing applications.

Handling 4-Sulfanylbenzoic acid requires the use of personal protective equipment (PPE) such as gloves and goggles. It should be conducted in a well-ventilated area or a fume hood to avoid inhalation of dust or vapor. Spills should be cleaned up with appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.