2-[(2E)-2-Buten-2-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(CAS: 91890-02-7)

2-[(2E)-2-Buten-2-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a colorless liquid with a molecular weight of approximately 244.36 g/mol. It has a low solubility in water but is readily soluble in organic solvents like ethanol and toluene. The compound is known for its reactivity in boronate ester formation and is stable under normal conditions, though it should be stored in a cool, dark place to maintain its properties.

2-[(2E)-2-Buten-2-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is synthesized via palladium-catalyzed allylic boronation of 2,3,3,3-tetramethyl-1-iodopropane with 2-butenyl boronic acid. The reaction is performed under mild conditions, providing a high yield and good selectivity. The use of a suitable ligand and base can enhance the reaction efficiency.

2-[(2E)-2-Buten-2-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is primarily used in the pharmaceutical industry for the synthesis of boron-containing drugs and functional materials. It also finds applications in the production of polymers, sensors, and in the semiconductor industry for photoresists and other materials.

When handling 2-[(2E)-2-Buten-2-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, it is important to use appropriate personal protective equipment (PPE), including gloves and safety goggles. The compound should be stored in a cool, dry place away from direct sunlight and heat sources. Spills should be cleaned up with appropriate absorbents, and the area should be well-ventilated. Always refer to the safety data sheet (SDS) for detailed handling and disposal instructions.