5-Bromo-4-pyrimidinamine(CAS: 1439-10-7)

5-Bromo-4-pyrimidinamine (CAS: 1439-10-7) is a crystalline solid with a molecular weight of approximately 201.04 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol and acetone. The compound shows moderate reactivity, particularly towards nucleophiles, and is often used in organic synthesis due to its bromine substituent.

5-Bromo-4-pyrimidinamine is typically synthesized by bromination of 4-pyrimidinamine. This process involves treating 4-pyrimidinamine with bromine in the presence of a base like sodium hydroxide. Other methods include using bromine derivatives in organic solvents, with the reaction often being carried out under mild conditions to achieve good selectivity and high yield.

5-Bromo-4-pyrimidinamine (CAS: 1439-10-7) is primarily used in the pharmaceutical industry for the synthesis of various bioactive compounds. It also finds applications in polymer chemistry, where it can be used as a cross-linking agent. Additionally, it is utilized in the development of sensors and in semiconductor technology for specific chemical modifications.

When handling 5-Bromo-4-pyrimidinamine (CAS: 1439-10-7), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be stored in a cool, well-ventilated area away from heat sources and incompatible materials. In case of spills, they should be cleaned up using appropriate spill kits, and the area should be flushed with water. Always refer to the Safety Data Sheet (SDS) for detailed safety information.