2-Bromo-N-carbamoyl-3-methylbutanamide(CAS: 496-67-3)

2-Bromo-N-carbamoyl-3-methylbutanamide (CAS: 496-67-3) is a crystalline compound with a molecular weight of approximately 211.07 g/mol. It has a melting point of 140-142°C and a solubility in water of 0.025 g/100 mL at 20°C. This compound shows moderate reactivity in nucleophilic substitution reactions and is stable under normal storage conditions.

2-Bromo-N-carbamoyl-3-methylbutanamide (CAS: 496-67-3) is typically synthesized through a multi-step process involving the bromination of 3-methylbutanamide followed by carbamoylation. The synthesis involves the use of bromine in the presence of a suitable base and a catalyst. The process yields a compound with high purity and good selectivity.

2-Bromo-N-carbamoyl-3-methylbutanamide (CAS: 496-67-3) is used in various industries, including pharmaceuticals for the synthesis of certain drugs, and in chemical research for its reactivity in organic synthesis. It also has applications in the polymer industry for modifying polymer properties and in the development of sensors and semiconductors.

When handling 2-Bromo-N-carbamoyl-3-methylbutanamide (CAS: 496-67-3), it is important to use proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure to vapors. Spills should be handled by disconnecting sources of ignition, neutralizing with a suitable base, and disposing of the waste according to local regulations. Safety data sheets (SDS) should be consulted for detailed guidance.