1,3-Difluoro-2-methyl-4-nitrobenzene(CAS: 79562-49-5)

1,3-Difluoro-2-methyl-4-nitrobenzene is a solid at room temperature with a crystalline form. It has a molecular weight of approximately 193.06 g/mol. The compound is slightly soluble in water but more soluble in organic solvents such as ethanol and acetone. It shows reactivity towards nucleophilic substitution and electrophilic aromatic substitution reactions.

1,3-Difluoro-2-methyl-4-nitrobenzene is commonly synthesized through the nitration of 2-methyl-4-fluorobenzoic acid. The reaction typically involves the use of nitric acid and sulfuric acid as the nitrating agent. The yield is around 85%, and the product can be isolated using recrystallization techniques.

1,3-Difluoro-2-methyl-4-nitrobenzene is utilized in various industries, including pharmaceuticals, where it serves as a precursor for the synthesis of active pharmaceutical ingredients. It also finds applications in the manufacturing of dyes, pigments, and as an intermediate in the production of semiconductors and sensors.

When handling 1,3-Difluoro-2-methyl-4-nitrobenzene, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be used in a well-ventilated area or within a fume hood to minimize exposure. In case of a spill, contain the material using appropriate absorbents and follow the safety data sheet (SDS) for disposal. Storage should be in a cool, dry place away from direct sunlight and sources of ignition.