Xylometazoline HCl (Oxymetazoline EP Impurity B HCl)(CAS: 1218-35-5)

Xylometazoline HCl (CAS: 1218-35-5) is a hydrochloride salt of xylometazoline, a compound classified as an alpha-2 adrenergic agonist. It appears as a white crystalline powder, soluble in water, and is commonly recognized as an impurity in the synthesis of oxymetazoline, a decongestant used in pharmaceuticals. Its chemical formula is C10H13NO2·HCl.

Xylometazoline HCl (CAS: 1218-35-5) is primarily used in pharmaceutical quality control to identify impurities during the production of oxymetazoline. It also serves as a research tool for analytical studies and may be employed in industrial processes related to drug synthesis. However, it is not used as a standalone medication or additive in consumer products.

Xylometazoline HCl (CAS: 1218-35-5) is generally considered safe when handled properly in controlled environments. It has low toxicity but requires standard safety measures such as wearing gloves and goggles to prevent skin or eye contact. Safety data sheets (SDS) recommend avoiding ingestion and following OSHA guidelines for chemical handling. Its use as an impurity is regulated under pharmaceutical safety standards.

Xylometazoline HCl (CAS: 1218-35-5) should be stored in a cool, dry place (ideally below 25°C), in airtight containers to prevent moisture exposure. It is sensitive to light, so storage in opaque containers or dark environments is recommended. Maintain low humidity levels to ensure stability and avoid degradation over time.