2-Chloro-6-nitroaniline(CAS: 769-11-9)

2-Chloro-6-nitroaniline is a white or off-white crystalline solid with a molecular weight of 186.58 g/mol. It is slightly soluble in water and has good solubility in organic solvents like ethanol and acetone. It is known for its reactive nature, specifically towards nucleophilic substitution and electrophilic aromatic substitution reactions.

2-Chloro-6-nitroaniline is typically synthesized via the nitration of 2-chloroaniline. The reaction is conducted using a mixture of concentrated nitric acid and sulfuric acid as the nitrating agent. The product is usually isolated by recrystallization from suitable solvents.

2-Chloro-6-nitroaniline is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It is also used in the production of dyes and pigments, and has applications in the agricultural and textile industries. Additionally, it is utilized in the synthesis of some analytical sensors and as a precursor in organic semiconductor materials.

When handling 2-Chloro-6-nitroaniline, it is important to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from heat and ignition sources. In case of a spill, it should be handled in a fume hood, and the area should be well-ventilated. It is advisable to consult the Safety Data Sheet (SDS) for specific handling and disposal guidelines.