2-Bromo-1-cyclopropylethanone(CAS: 69267-75-0)

2-Bromo-1-cyclopropylethanone (CAS: 69267-75-0) is a white crystalline solid. Its molecular weight is approximately 152.01 g/mol. It is slightly soluble in water but readily soluble in organic solvents like ethanol and acetone. This compound is known for its reactivity, particularly towards nucleophiles, and it is less reactive than its bromine analogs in other positions.

2-Bromo-1-cyclopropylethanone (CAS: 69267-75-0) can be synthesized via a cyclopropanation reaction of ethyl acetoacetate with bromoalkene or bromoalkyne in the presence of a suitable catalyst. The reaction provides good selectivity and yields. Common catalysts include palladium complexes and ligands.

2-Bromo-1-cyclopropylethanone (CAS: 69267-75-0) is used in the pharmaceutical industry for the synthesis of certain drugs, in polymer chemistry for functionalization, and in the production of sensors for detecting specific compounds. It also finds application in the preparation of semiconductors and other advanced materials.

When handling 2-Bromo-1-cyclopropylethanone (CAS: 69267-75-0), it is essential to use appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood. Spills should be cleaned up promptly with absorbent materials, and proper disposal should follow the guidelines in the Safety Data Sheet (SDS).