N-(4-Formylphenyl)methanesulfonamide(CAS: 83922-54-7)

N-(4-Formylphenyl)methanesulfonamide is a white crystalline solid with a molecular weight of approximately 264.25 g/mol. It is sparingly soluble in water but soluble in organic solvents like methanol and ethyl acetate. The compound is known for its moderate reactivity, particularly towards nucleophilic substitution reactions.

N-(4-Formylphenyl)methanesulfonamide is typically synthesized via a multi-step process involving the formation of an intermediate methanesulfonamide followed by alkylation of a phenol to form the formylated product. Commonly, this involves the use of sodium methanesulfonate and formylated phenol in the presence of a base like sodium hydroxide, followed by acidification to yield the desired compound.

N-(4-Formylphenyl)methanesulfonamide is used in various industries, including pharmaceuticals for its potential as a precursor in drug synthesis, and in polymer chemistry as a functional monomer. It also finds applications in the production of sensors and semiconductors, where its chemical properties are exploited.

When handling N-(4-Formylphenyl)methanesulfonamide, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Ensure the use of a fume hood to minimize exposure. Store the compound in a cool, dry place away from heat sources. In case of a spill, immediately clean up with absorbent materials and follow standard laboratory safety protocols. For detailed safety information, refer to the Safety Data Sheet (SDS).