Methyl 5-methyl-1,3-oxazole-4-carboxylate(CAS: 41172-57-0)

Methyl 5-methyl-1,3-oxazole-4-carboxylate is a crystalline compound with a molecular weight of approximately 154.17 g/mol. It is slightly soluble in water but more soluble in organic solvents. It exhibits low reactivity, primarily undergoing nucleophilic substitution reactions. It has a melting point of about 43-45 °C.

Methyl 5-methyl-1,3-oxazole-4-carboxylate is typically synthesized via the condensation of methyl acetate and 5-methyl-1,3-oxazoline-4-one in the presence of a catalytic amount of an acid, such as phosphoric acid. The reaction is conducted under mild conditions to achieve good yield and selectivity.

Methyl 5-methyl-1,3-oxazole-4-carboxylate is used in the pharmaceutical industry as a precursor for drug synthesis. It also finds applications in the polymer industry as a monomer and in sensor technology for its unique chemical properties.

When handling Methyl 5-methyl-1,3-oxazole-4-carboxylate, it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. It should be stored in a cool, dry place away from direct sunlight. In case of a spill, use a fume hood and appropriate spill cleanup materials. Refer to the Safety Data Sheet (SDS) for detailed handling and safety information.