Cyclosporin A(CAS: 59865-13-3)

Cyclosporin A is a cyclic undecapeptide immunosuppressant drug. It has the chemical formula C43H67NO12 and is known for its ability to inhibit T-cell activation. Cyclosporin A is used in medical treatments to prevent organ rejection and manage autoimmune diseases. It is also recognized for its high molecular weight and unique structure, which contribute to its pharmacological activity.

Cyclosporin A is primarily used in immunosuppressive therapy to prevent organ rejection after transplantation. It is also prescribed for the treatment of autoimmune conditions such as rheumatoid arthritis and lupus. Additionally, it is used in research to study immune system modulation and in veterinary medicine for certain inflammatory disorders. Its applications span pharmaceutical, medical, and research fields.

Cyclosporin A is generally safe when used as directed under medical supervision. However, it can cause side effects such as nephrotoxicity, hypertension, and gastrointestinal issues. Proper handling, including wearing protective gloves and avoiding contact with skin or mucosa, is recommended. Safety standards ensure its controlled use in pharmaceuticals and research to minimize risks.

Cyclosporin A should be stored in a cool, dry place away from direct light. It is typically kept at a temperature between 15°C to 25°C (59°F to 77°F) and requires a humidity level below 60% to maintain stability. It should be stored in a sealed container and protected from moisture and light to preserve its potency and effectiveness.