4,4-Diethoxy-N-methylbutan-1-amine(CAS: 114094-45-0)

4,4-Diethoxy-N-methylbutan-1-amine (CAS: 114094-45-0) is a colorless oil at room temperature. Its molecular weight is approximately 220.31 g/mol. It is slightly soluble in water but miscible with organic solvents such as ethanol and acetone. The compound shows low reactivity under normal conditions but can undergo nucleophilic substitution reactions. It has a pKa of around 8.5, indicating basic properties.

4,4-Diethoxy-N-methylbutan-1-amine (CAS: 114094-45-0) is typically synthesized via a multistep procedure involving the reaction of methyl chloroformate with ethylamine to form N-methylformamide. This intermediate is then treated with diethyl ether to produce the desired amine. The reaction is catalyzed by a base such as sodium hydride, and the overall yield is around 75%. The process involves careful temperature control to avoid side reactions.

4,4-Diethoxy-N-methylbutan-1-amine (CAS: 114094-45-0) is primarily used in the pharmaceutical industry as a precursor in the synthesis of several drugs. It also finds applications in polymer synthesis for the development of special coatings and adhesives. Additionally, it is utilized in the production of sensors and semiconductors for electronic devices due to its specific functional groups.

When handling 4,4-Diethoxy-N-methylbutan-1-amine (CAS: 114094-45-0), it is essential to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Store the compound in a well-ventilated and cool area, away from direct sunlight and heat sources. In case of spill, neutralize with an appropriate reagent and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.